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Book Details :
Published on: 2010-12-01
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Original language: English

Severe inflammation of the kidney can indicate the serious, negative prognosis of lupus nephritis when present in conjunction with systemic lupus erythematosus (SLE), a chronic autoimmune connective tissue disease that can affect any part of the body, most often harming the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. This book pulls together in one comprehensive reference the current knowledge regarding the inherited and immunologic abnormalities that have been identified in SLE, with specific reference to the development of renal disease and the way in which these factors may impact upon the chronic care of these patients. Since publication of the first edition in 1999, the discipline of medicine has experienced some revolutionary changes in the way drugs are used to treat to immune system diseases. On the basis of careful analysis of physical make-up, the immune system, and microscopic features of the human body, it has become clear that multiple components of the immune system are responsible for renal injury and that any given patient can experience a combination of these mechanisms. With this in mind, specific therapies can be tested, and drugs that interrupt the immune response in highly specific ways are being scrutinized for their value in lupus nephritis. This new edition reflects the updated methods of classification and advances in treatment options for SLE, and covers recent clinical trials to help treat patients using the most up-to-date knowledge available. It takes a practical approach throughout, and will be of interest to those working with patients with lupus nephritis, and those who manage their everyday care. Systemic Lupus Erythematosus NEJM To the clinician systemic lupus erythematosus is important because it is a potentially fatal disease that is easily confused with many other disorders. Membranous Lupus Nephritis: The Same But Different ... Membranous lupus nephritis (MLN) has a favorable prognosis compared to proliferative lupus nephritis (PLN) or combined MLN/PLN although a significant proportion of ... Rituximab (Rituxan) - Aetna Number: 0314. Policy. Aetna considers rituximab (Rituxan) medically necessary for any of the following indications: Acute lymphoid leukemia (induction/consolidation ... Mycophenolate versus Azathioprine as Maintenance Therapy ... Original Article. Mycophenolate versus Azathioprine as Maintenance Therapy for Lupus Nephritis. Mary Anne Dooley M.D. M.P.H. David Jayne M.D. Ellen M. Ginzler M ... Renal involvement in primary Sjogren syndrome : Nature ... a Masson trichrome staining of a kidney biopsy sample from a patient with primary Sjgren syndrome (pSS) and tubulointerstitial nephritis (magnification 100). Systemic Lupus Erythematosus - clevelandclinicmeded.com Definition. Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease that has a broad range of clinical manifestations. In SLE tissue damage in multiple ... Lupus Nephritis Treatment & Management: Approach ... Lupus nephritis one of the most serious manifestations of systemic lupus erythematosus (SLE) usually arises within 5 years of diagnosis; however renal ... Henoch-Schnlein Purpura Nephritis: Pathophysiology ... Summary. Henoch-Schnlein purpura nephritis is a rare kidney disease leading to chronic kidney disease in a non-negligible percentage of patients. Systemic Lupus Erythematosus (SLE) Medication ... Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that has protean manifestations and follows a relapsing and remitting course. More ... Systemic Lupus Erythematosus (SLE): Treatment ... - Medscape Abstract and Introduction Abstract. Purpose of review The pathogenesis of systemic lupus erythematosus (SLE) involves aberrancy in multiple components of the immune ...
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